This antibody reacts with human GFAP.
It shows no cross-reaction with other intermediate filaments. Anti-GFAP stains
astrocytes, ependymal cells and corresponding tumors. GFAP is useful for
distinguishing neoplasms of astrocytic origin and is useful n differentiating
gliomas from metastatic lesions in the brain. Neuroblastomas, Schwannomas, as
well as extra-CNS tumors are not labeled. Negative staining has been observed
with lymphatic tissue, muscle, gastrointestinal tract, liver, kidney, pancreas
and bladder.